Signal Peptide Database

Signal Peptide Database - Drosophila melanogaster

Entry Details

Source Database

UniProtKB/Swiss-Prot

UniProtKB/Swiss-Prot Accession Number

P17644 (Created: 1990-08-01 Updated: 2008-12-16)

UniProtKB/Swiss-Prot Entry Name

ACH2_DROME

Protein Name

Acetylcholine receptor subunit alpha-like 2

Gene

nAcRalpha-96Ab

Organism Scientific

Drosophila melanogaster

Organism Common

Fruit fly

Lineage

Eukaryota
  Metazoa
    Arthropoda
      Hexapoda
        Insecta
          Pterygota
            Neoptera
              Endopterygota
                Diptera
                  Brachycera
                    Muscomorpha
                      Ephydroidea
                        Drosophilidae
                          Drosophila
                            Sophophora

Protein Length [aa]

576

Protein Mass [Da]

65506

Features

TypeDescriptionStatusStartEnd
signal peptide      probable   1   21
chain   Acetylcholine receptor subunit alpha-like 2      22   576
disulfide bond      by similarity   169   183
disulfide bond   Associated with receptor activation   by similarity   243   244
transmembrane region      potential   262   285
transmembrane region      potential   293   311
transmembrane region      potential   327   346
transmembrane region      potential   527   545
topological domain   Extracellular   potential   22   261
topological domain   Cytoplasmic   potential   347   526
glycosylation site   N-linked (GlcNAc...)   potential   65   65
glycosylation site   N-linked (GlcNAc...)   potential   254   254
glycosylation site   N-linked (GlcNAc...)   potential   570   570

SP Length

----+----1----+----2----+----3----+----4----+----5

Signal Peptide

MAPGCCTTRPRPIALLAHIWR

Sequence

MAPGCCTTRPRPIALLAHIWRHCKPLCLLLVLLLLCETVQANPDAKRLYD
DLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHE
WQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAI
LHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLK
HISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPD
IFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISIL
LSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHY
RKPSTHKMRPWIRSFFIKRLPKLLLMRVPKDLLRDLAANKINYGLKFSKT
KFGQALMDEMQMNSGGSSPDSLRRMQGRVGAGGCNGMHVTTATNRFSGLV
GALGGGLSTLSGYNGLPSVLSGLDDSLSDVAARKKYPFELEKAIHNVMFI
QHHMQRQDEFNAEDQDWGFVAMVMDRLFLWLFMIASLVGTFVILGEAPSL
YDDTKAIDVQLSDVAKQIYNLTEKKN

Original

----+----1----+----2----+----3----+----4----+----5

Hydropathies

Signal Peptide Website